G. E. ZURENKO: search on Z-Library

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1

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Sahay, Gaurav, Querbes, William, Alabi, Christopher, Eltoukhy, Ahmed, Sarkar, Sovan, Zurenko, Christopher, Karagiannis, Emmanouil, Love, Kevin, Chen, Delai, Zoncu, Roberto, Buganim, Yosef, Schroeder,

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

2

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

Lee, Hyukjin, Lytton-Jean, Abigail K. R., Chen, Yi, Love, Kevin T., Park, Angela I., Karagiannis, Emmanouil D., Sehgal, Alfica, Querbes, William, Zurenko, Christopher S., Jayaraman, Muthusamy, Peng, C

Journal:

Nature Nanotechnology

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

3

Novel oxazolidinone–quinolone hybrid antimicrobials

Mikhail F. Gordeev, Corinne Hackbarth, Michael R. Barbachyn, Lee S. Banitt, James R. Gage, Gary W. Luehr, Marcela Gomez, Joaquim Trias, Sara E. Morin, Gary E. Zurenko, Christian N. Parker, Jonathan M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

4

ChemInform Abstract: Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections.

S. J. BRICKNER, D. K. HUTCHINSON, M. R. BARBACHYN, P. R. MANNINEN, D. A. ULANOWICZ, S. A. GARMON, K. C. GREGA, S. K. HENDGES, D. S. TOOPS, C. W. FORD, G. E. ZURENKO

Journal:

Year:

1996

File:

PDF, 35 KB

1996

5

Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition

Atli Thorarensen, Martin R. Douglas, Jr., Douglas C. Rohrer, Anne F. Vosters, Anthony W. Yem, Vincent D. Marshall, Janet C. Lynn, Michael J. Bohanon, Paul K. Tomich, Gary E. Zurenko, Michael T. Sweene

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 655 KB

english, 2001

6

In vitroActivity of Linezolid and Eperezolid, Two Novel Oxazolidinone Antimicrobial Agents, Against Anaerobic Bacteria

Betty H. Yagi, Gary E. Zurenko

Journal:

Year:

1997

Language:

english

File:

PDF, 143 KB

english, 1997

7

Structure–activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors

J. Craig Ruble, Brian D. Wakefield, Gregg M. Kamilar, Keith R. Marotti, Earline Melchior, Michael T. Sweeney, Gary E. Zurenko, Donna L. Romero

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 140 KB

english, 2007

8

Benzisoxazolones: antimicrobial and antileukemic activity

Wierenga, W., Evans, B. R., Zurenko, G. E.

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 585 KB

english, 1984

9

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

Shaw, K. J., Poppe, S., Schaadt, R., Brown-Driver, V., Finn, J., Pillar, C. M., Shinabarger, D., Zurenko, G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 499 KB

english, 2008

10

Evaluation of the Effect of Bacterial Efflux Pumps on the Antibacterial Activity of the Novel Fluoroquinolone Besifloxacin

Shinabarger, D.L., Zurenko, G.E., Hesje, C.K., Sanfilippo, C.M., Morris, T.W., Haas, W.

Journal:

Journal of Chemotherapy

Year:

2011

Language:

english

File:

PDF, 378 KB

english, 2011

11

ChemInform Abstract: PTILOCAULIN AND ISOPTILOCAULIN, ANTIMICROBIAL AND CYTOTOXIC CYCLIC GUANIDINES FROM THE CARIBBEAN SPONGE PTILOCAULIS AFF. P. SPICULIFER (LAMARCK, 1814)

HARBOUR, G. C., TYMIAK, A. A., RINEHART, K. L. JUN., SHAW, P. D., HUGHES, R. G. JUN., MIZSAK, S. A., COATS, J. H., ZURENKO, G. E., LI, L. H., KUENTZEL, S. L.

Journal:

Chemischer Informationsdienst

Year:

1981

File:

PDF, 114 KB

1981

12

Corrigendum to “Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition” [Bioorg. Med. Chem. Lett. 11 (2001) 1355]†

Atli Thorarensen, Martin R. Deibel Jr., Douglas C. Rohrer, Anne F. Vosters, Anthony W. Yem, Vincent D. Marshall, Janet C. Lynn, Michael J. Bohanon, Paul K. Tomich, Gary E. Zurenko, Michael T. Sweeney,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 55 KB

english, 2001

13

In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent

Schaadt, R., Sweeney, D., Shinabarger, D., Zurenko, G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

14

Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics

Cory Stiff, David R. Graber, Atli Thorarensen, Brian D. Wakefield, Keith R. Marotti, Earline P. Melchior, Michael T. Sweeney, Fusen Han, Douglas C. Rohrer, Gary E. Zurenko, Donna L. Romero

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 221 KB

english, 2008

15

Synthesis and antibacterial activity of new tropone-substituted phenyloxazolidinone antibacterial agents 1. Identification of leads and importance of the tropone substitution pattern

Michael R. Barbachyn, Dana S. Toops, Debra A. Ulanowicz, Kevin C. Grega, Steven J. Brickner, Charles W. Ford, Gary E. Zurenko, Judith C. Hamel, Ronda D. Schaadt, Douglas Stapert, Betty H. Yagi, Jerry

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 278 KB

english, 1996

16

The synthesis and antibacterial activity of 1,3,4-Thiadiazole phenyl oxazolidinone analogues

Lisa M Thomasco, Robert C Gadwood, Elizabeth A Weaver, Jason M Ochoada, Charles W Ford, Gary E Zurenko, Judith C Hamel, Douglas Stapert, Judy K Moerman, Ronda D Schaadt, Betty H Yagi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

17

ChemInform Abstract: U-87947E (I), a Potent Quinolone Antibacterial Agent Incorporating a Bicyclo(1.1.1)pent-1-yl (BCP) Subunit.

M. R. BARBACHYN, D. K. HUTCHINSON, D. S. TOOPS, R. J. REID, G. E. ZURENKO, B. H. YAGI, R. D. SCHAADT, J. W. ALLISON

Journal:

Year:

1995

File:

PDF, 27 KB

1995

18

An in vitro time-kill assessment of linezolid and anaerobic bacteria

Betty H. Yagi, Gary E. Zurenko

Journal:

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

19

Synthesis and antibacterial activity of new tropone-substituted phenyloxazolidinone antibacterial agents 2. Modification of the phenyl ring — the potentiating effect of fluorine substitution on in vivo activity

Michael R. Barbachyn, Dana S. Toops, Kevin C. Grega, Susan K. Hendges, Charles W. Ford, Gary E. Zurenko, Judith C. Hamel, Jonda D. Schaadt, Douglas Stapert, Betty H. Yagi, Jerry M. Buysse, William F.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 284 KB

english, 1996

20

N-Acyl 3-alkylidenyl- and 3-alkyl azetidin-2-ones: A new class of monocyclic .BETA.-lactam antibacterial agents. 1. Structure-activity relationships of 3-isopropylidene and 3-isopropyl analogs.

BRICKNER, STEVEN J., GAIKEMA, JEFFREY J., ZURENKO, GARY E., GREENFIELD, LAURA J., MANNINEN, PETER R., ULANOWICZ, DEBRA A.

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 676 KB

english, 1992

21

Piperazinyl Oxazolidinone Antibacterial Agents Containing a Pyridine, Diazene, or Triazene Heteroaromatic Ring

Tucker, John A., Allwine, Debra A., Grega, Kevin C., Barbachyn, Michael R., Klock, Jennifer L., Adamski, Jenifer L., Brickner, Steven J., Hutchinson, Douglas K., Ford, Charles W., Zurenko, Gary E., Co

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

22

Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials

Paul D. Johnson, Paul A. Aristoff, Gary E. Zurenko, Ronda D. Schaadt, Betty H. Yagi, Charles W. Ford, Judith C. Hamel, Douglas Stapert, Judy K. Moerman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 198 KB

english, 2003

23

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Fred L Ciske, Michael R Barbachyn, Michael J Genin, Kevin C Grega, Chi Sing Lee, Lester A Dolak, Eric P Seest, William Watt, Wade J Adams, Janice M Friis, Charles W Ford, Gary E Zurenko

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

24

In vitro antibacterial activity and interactions with beta-lactamases and penicillin-binding proteins of the new monocarbam antibiotic U-78608.

Zurenko, G E, Truesdell, S E, Yagi, B H, Mourey, R J, Laborde, A L

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1990

Language:

english

File:

PDF, 1.05 MB

english, 1990

25

In vitro activity of cefpodoxime proxetil (U-76,252; CS-807) against Neisseria gonorrhoeae.

Schaadt, R D, Yagi, B H, Zurenko, G E

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1990

Language:

english

File:

PDF, 339 KB

english, 1990

26

The isolation and characterization of rubradirin B.

HOEKSEMA, H., LEWIS, C., MIZSAK, S. A., SHILEY, J. A., WAIT, D. R., WHALEY, H. A., ZURENKO, G. E.

Journal:

The Journal of Antibiotics

Year:

1978

Language:

english

File:

PDF, 1.50 MB

english, 1978

27

ChemInform Abstract: Synthesis and Antibacterial Activity of [6,5,5] and [6,6,5] Tricyclic Fused Oxazolidinones.

D. M. GLEAVE, S. J. BRICKNER, P. R. MANNINEN, D. A. ALLWINE, K. D. LOVASZ, D. C. ROHRER, J. A. TUCKER, G. E. ZURENKO, C. W. FORD

Journal:

Year:

1998

File:

PDF, 32 KB

1998

28

Serum inhibitory titers and serum bactericidal titers for human subjects receiving multiple doses of the antibacterial oxazolidinones eperezolid and linezolid

Ronda D. Schaadt, Donald H. Batts, Peter T. Daley-Yates, Steven D. Pawsey, Dennis J. Stalker, Gary E. Zurenko

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1997

Language:

english

File:

PDF, 394 KB

english, 1997

29

Ptilocaulin and isoptilocaulin, antimicrobial and cytotoxic cyclic guanidines from the Caribbean sponge Ptilocaulis aff. P. spiculifer (Lamarck, 1814)

Harbour, Gary C., Tymiak, Adrienne A., Rinehart, Kenneth L., Shaw, Paul D., Hughes, Robert, Mizsak, Stephen A., Coats, John H., Zurenko, Gary E., Li, Li H., Kuentzel, Sandra L.

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 343 KB

english, 1981

30

Prediction of bacterial susceptibility to cefpodoxime by using the ceftriaxone minimum inhibitory concentration result

Ronald N. Jones, Gary E. Zurenko

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1993

Language:

english

File:

PDF, 335 KB

english, 1993

31

Chemical modification of aminoglycosides. 3. Synthesis of 2"-deoxykanamycins from neamine

Reid, R. J., Mizsak, S. A., Reineke, L. M., Zurenko, G. E., Stern, K. F., Magerlein, B. J.

Journal:

Journal of Medicinal Chemistry

Year:

1981

Language:

english

File:

PDF, 814 KB

english, 1981

32

Discovery and Characterization of QPT-1, the Progenitor of a New Class of Bacterial Topoisomerase Inhibitors

Miller, A. A., Bundy, G. L., Mott, J. E., Skepner, J. E., Boyle, T. P., Harris, D. W., Hromockyj, A. E., Marotti, K. R., Zurenko, G. E., Munzner, J. B., Sweeney, M. T., Bammert, G. F., Hamel, J. C., F

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

33

ChemInform Abstract: Enols as Potent Antibacterial Agents.

Atli Thorarensen, Gary E. Zurenko, Michael T. Sweeney, Keith R. Marotti, Timothy P. Boyle

Journal:

Year:

2002

File:

PDF, 29 KB

2002

34

New Antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones

Upinder Singh, B Raju, Stuart Lam, Joseph Zhou, Robert C Gadwood, Charles W Ford, Gary E Zurenko, Ronda D Schaadt, Sara E Morin, Wade J Adams, Janice M Friis, Maria Courtney, Joe Palandra, Corinne J H

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 208 KB

english, 2003

35

Oxazolidinone antibacterial agents: development of the clinical candidates eperezolid and linezolid

Zurenko, Gary E, Ford, Charles W, Hutchinson, Douglas K, Brickner, Steven J, Barbachyn, Micheal R

Journal:

Expert Opinion on Investigational Drugs

Year:

1997

Language:

english

File:

PDF, 156 KB

english, 1997

36

Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings

Atli Thorarensen, Brian D. Wakefield, Donna L. Romero, Keith R. Marotti, Michael T. Sweeney, Gary E. Zurenko, Douglas C. Rohrer, Fusen Han, Garold L. Bryant Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

37

Estimating the postantibiotic effect: A two-phase mathematical model

Marshall N. Brunden, Betty H. Yagi, Michael S. Lajiness, Gary E. Zurenko

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 554 KB

english, 1991

38

Modification of the error-rate bounded classification scheme for use with two MIC break points

Brunden, Marshall N., Zurenko, Gary E., Kapik, Barry

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1992

Language:

english

File:

PDF, 466 KB

english, 1992

39

ChemInform Abstract: BENZISOXAZOLONES: ANTIMICROBIAL AND ANTILEUKEMIC ACTIVITY

WIERENGA, W., EVANS, B. R., ZURENKO, G. E.

Journal:

Chemischer Informationsdienst

Year:

1985

File:

PDF, 104 KB

1985

40

ChemInform Abstract: 3-Arylpiperidines as Potentiators of Existing Antibacterial Agents.

Atli Thorarensen, Alice L. Presley-Bodnar, Keith R. Marotti, Timothy P. Boyle, Charlotte L. Heckaman, Michael J. Bohanon, Paul K. Tomich, Gary E. Zurenko, Michael T. Sweeney, Betty H. Yagi

Journal:

Year:

2001

File:

PDF, 28 KB

2001

41

Synthesis and Biological Evaluation of Benzazepine Oxazolidinone Antibacterials.

Paul D. Johnson, Paul A. Aristoff, Gary E. Zurenko, Ronda D. Schaadt, Betty H. Yagi, Charles W. Ford, Judith C. Hamel, Douglas Stapert, Judy K. Moerman

Journal:

Year:

2004

File:

PDF, 148 KB

2004

42

Preparation of novel anthranilic acids as antibacterial agents: Extensive evaluation of structural and physical properties on antibacterial activity and human serum albumin affinity

Atli Thorarensen, Jianke Li, Brian D. Wakefield, Donna L. Romero, Keith R. Marotti, Michael T. Sweeney, Gary E. Zurenko, Ronald W. Sarver

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 185 KB

english, 2007

43

3-Arylpiperidines as potentiators of existing antibacterial agents

Atli Thorarensen, Alice L Presley-Bodnar, Keith R Marotti, Timothy P Boyle, Charlotte L Heckaman, Michael J Bohanon, Paul K Tomich, Gary E Zurenko, Michael T Sweeney, Betty H Yagi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 283 KB

english, 2001

44

U-87947E, a protein quinolone antibacterial agent incorporating a bicyclo[1.1.1]pent-1-yl (BCP) subunit

Michael R. Barbachyn, Douglas K. Hutchinson, Dana S. Toops, Raymond J. Reid, Gary E. Zurenko, Betty H. Yagi, Ronda D. Schaadt, John W. Allison

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 402 KB

english, 1993

45

Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors

Cory M. Stiff, Min Zhong, Ronald W. Sarver, Hua Gao, Andrea M. Ho, Michael T. Sweeney, Gary E. Zurenko, Donna L. Romero

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 140 KB

english, 2007

46

In Vitro Activities of Linezolid Combined with Other Antimicrobial Agents against Staphylococci, Enterococci, Pneumococci, and Selected Gram-Negative Organisms

Sweeney, M. T., Zurenko, G. E.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2003

Language:

english

File:

PDF, 67 KB

english, 2003

47

In vitro antibacterial activity of trospectomycin (U-63366F), a novel spectinomycin analog.

Zurenko, G E, Yagi, B H, Vavra, J J, Wentworth, B B

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1988

Language:

english

File:

PDF, 1.24 MB

english, 1988

48

In vitro activities of U-100592 and U-100766 , novel oxazolidinone antibacterial agents . In Vitro Activities of U-100592 and U-100766 , Novel Oxazolidinone Antibacterial Agents

Zurenko, G E, Yagi, B H, Schaadt, R D, Allison, J W, Kilburn, J O, Glickman, E, Hutchinson, D K, Barbachyn, M R, Brickner, S J, Zurenko, Gary E, Yagi, Betty H, Schaadt, Ronda D, Allison, John W, Kilbu

Year:

1996

Language:

english

File:

PDF, 237 KB

english, 1996

49

Enols as Potent Antibacterial Agents

Atli Thorarensen, Gary E. Zurenko, Michael T. Sweeney, Keith R. Marotti, Timothy P. Boyle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

50

Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Potent Antibacterial Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

Genin, Michael J., Hutchinson, Douglas K., Allwine, Debra A., Hester, Jackson B., Emmert, D. Edward, Garmon, Stuart A., Ford, Charles W., Zurenko, Gary E., Hamel, Judith C., Schaadt, Ronda D., Stapert

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

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